Artigos Científicos


  1. de Oliveira, P. D. et al. Ozonolysis of neem oil: Preparation and characterization of potent antibacterial agents against multidrug resistant bacterial strainsRSC Advances 2017, 7, 34356-34365
  2. Braga, F. C; Avvari, N. P.; Gomes, R. S.; Nascimento, V. A.;  Oliveira, S. L.; Caires, A. R.L.; de Lima, D. P.; Beatriz, A. Design, synthesis and fluorescence analysis of potential fluorescent markers based on cardanol and glycerol.  Dyes and Pigments 2017, 141, 235-244.
  3. de Lima, D. P.; Giannesi, G.; Santos, E. A. ; Lopes, R. S.; Beatriz, A. et al. N-Acetylation of Aromatic Amines by the Soil Fungus Aspergillus japonicus (UFMS 48.136). Letters in Organic Chemistry. In Press 2017.
  4. de Araújo, F. GH. S.; de Figueiredo, D. R.; Auharek, S. A; Pesarini, J. R.; Meza, A.; Gomes, R. S.; Monreal, A. C. D.; Antoniolli-Silva, A. C. M. B.; de Lima, D. P.; Kassuya, C. A. L.; Beatriz, A.; Oliveira, R. J. In vivo Chemotherapeutic Insight of a Novel Isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation. Genetics and Molecular Biology. In Press, 2017.
  5. Paiva, D. R.; De Lima, D. P.; Avvari, N. P. ; Arruda, E. J.; Cabrini, I.; Marques, M. R.; Santos, E. A.; Biaggio, F. C.; Sangi, D. P.; Beatriz, A. A potent larvicidal agent against Aedes aegypti mosquito from cardanol. Anais da Academia Brasileira de Ciências 2017, 89, 373-382.
  6. Berno, C. R.; Rós, B. T.; da Silveira, I. O. M. F.; Coelho, H. R.; Antoniolli-Silva, A. C. M. B.; Beatriz, A.; de Lima, D. P.; Monreal, A. C. D.; Sousa, F. G.; Gomes, R. S.; Oliveira, R. J. 4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2016, 805,  19–24.
  7. Schneider, B. U. C.; De Souza, A. M.; Beatriz, A.; Carvalho, P. C.; Mauro, M. O.; Karaziack, C. B.; De Lima, D. P.; Oliveira, R. J. Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide. Genetics and Molecular Biology 2016, 39, 2, 279-289
  8. Micheletti, A. C.; Honda, N. K.; Carvalho, N. C. P.; De Lima, D. P.; Beatriz, A. Design, Synthesis and in vitro Antimicrobial Activity Evaluation of Novel Hybrids of Lichexantone-THC Derivatives. Orbital: Electron. J. Chem. 2015, 7, 301.
  9. Kogawa, N. R. A.; De Arruda, E. J.; Micheletti, A. C.; Matos, M. F. C.; De Oliveira, L. C. S.; De Lima, D. P.; Carvalho, N. C. P.; Oliveira, P. D.; Cunha, M. C.; Ojeda, M.; Beatriz, A. Synthesis, characterization, thermal behavior and biological activity of ozonides from vegetable oils. RSC Advances: an international journal to further the chemical sciences, 2015, 5, 65427 – 65436.
  10. Meza, A.; dos Santos, E. dos A.; Gomes, R. S. ; De Lima, D. P. ; Beatriz, A. Cytosporones: Isolation, Synthesis and Biological Activities of a Promising Class of Phenolic Lipids. Current Organic Synthesis, 2015, 12 (5): 618-638.
  11. Oliveira, R. J.; Navarro, S. D.; De Lima, D. P.; Meza, A.; Pesarini, J. R.; Gomes, R. S.; Karaziack, C. B.; Mauro, M. O.; Cunha-Laura, A. L.; Monreal, A. C. D.; Romão, W.; Lacerda Júnior, V.; Beatriz, A. A novel cytosporone 3-Heptyl-4,6-dihydroxy-3H-isobenzofuran-1-one: synthesis; toxicological, apoptotic and immunomodulatory properties; and potentiation of mutagenic damage. BMC Cancer, 2015, 561, 1-15.
  12. Araújo, Y. J. K.; Avvari, N. P.; Paiva, D. R.; De Lima, D. P.; Beatriz, A. Synthesis and enzymatic resolution of racemic 2,3-epoxy propyl esters obtained from glycerol. Tetrahedron Letters, 2015, 56, 1696.
  13. Beatriz, A.; Gomes, R. S.; Constantino, M. G.; da Silva, G. V. J.; de OLIVEIRA, K. T. Synthesis of the Bicyclo[6.2.1]undecane Ring System by a Solvent-free Diels-Alder Reaction. Tetrahedron Letters, v. 55, p. 679-681, 2014.
  14. Navarro, S. D.; Beatriz, A.; Meza, A.; Pesarini, J. R.; Gomes, R. S.; Karaziack, C. B.; Laura, A. L. C.; Monreal, A. C. D.; Romão, W.; Lacerda Junior, V.; Mauro, M. O.; Oliveira, R. J. A new synthetic resorcinolic lipid 3-Heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one: evaluation of toxicology and ability to potentiate the mutagenic and apoptotic effects of cyclophosphamide. European Journal of Medicinal Chemistry, p. 132-142, 2014.
  15. Rizzo, P. V. S.; Boarin, L. A.; FREITAS, I. O. M.; Gomes, R. S.; Beatriz, A.; Rinaldi, A. W.; Domingues, N. L. C. The study of biocatalyzed thio-Michael reaction: a greener and multi-gram protocol. Tetrahedron Letters, v. 55, p. 430-434, 2014.
  16. Polonini, H. C.; Lopes, R. S.; Beatriz, A ; Gomes, R. S. ; Silva, A. O.; Lima, R. V.; Nunes, G. A.; Brandão, M. A. F.; Raposo, N. R. B.; De Lima, D. P. SYNTHESIS AND EVALUATION OF OCTOCRYLENE-INSPIRED COMPOUNDS FOR UV-FILTER ACTIVITY. Química Nova, v. 37, p. 1004-1009, 2014.
  17. Naujorks, A. A. S.; da Silva, A. O.; Lopes, R. S.; de Albuquerque, S.; Beatriz, A.; Marques, M. R.; de Lima, D. P. Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities. Organic & Biomolecular Chemistry, v. 13, p. 428-437, 2014.
  18. dos Santos, E. A.; Hamel, E.; Bai, R.; Buernett, J. C.; Tozatti, C. S. S.; Bogo, D.; Perdomo, R. T. ; Antunes, A. M. M.; Marques, M. M.; Matos, M. F. C.; de Lima, D. P. Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity. Bioorganic & Medicinal Chemistry Letters, v. 23, p. 4669-4673, 2013.
  19. Santos, E. A.; Prado, P. C.; Beatriz, A.; de Lima, D. P. Synthesis and biological activity of sulfur compounds showing structural analogy with combretastatin A-4. Química Nova, v. 36, p. 279-283, 2013.
  20. da Silva, A. O.; LOPES, R. S.; de Lima, R, V.; Tozatti, C. S. S.; Marques, M. R.; de Albuquerque, S.; Beatriz, A.; de Lima, D. P. Synthesis and biological activity against Trypanosoma cruzi of substituted 1,4-naphthoquinones. European Journal of Medicinal Chemistry, v. 60, p. 51-56, 2013.
  21. Micheletti, A. C.; Honda, N. K.; Pavan, F. R.; Leite, C. Q. F.; Matos, M. F. C.; Perdomo, R. T.; Bogo, D.; Alcântara, G. B.; Beatriz, A. Increment of Antimycobacterial Activity on Lichexanthone Derivatives. Medicinal Chemistry (Hilversum), v. 9, p. 904-910, 2013.
  22. Magalhães, H. I. F.; Wilke, D. V.; Bezerra, D. P.; Cavalcanti, B. C.; Rotta, R.; de Lima, D. P.; Beatriz, A.; de Moraes, M. O.; Diniz Filho, J.; Pessoa, C. O. (4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells. Toxicology and Applied Pharmacology, v. 272, p. 117-126, 2013.
  23. Zamberlam, C. E. M.; Meza, A.; Leite, C. B.; Marques, M. R.; de Lima, D. P.; Beatriz, A. Total synthesis and allelopathic activity of cytosporones A-C. Journal of the Brazilian Chemical Society, v. 23, p. 124-131, 2012.
  24. Martins, L. R.; Beatriz, A.; de Lima, D. P. Symmetrical molecules from reaction of beta-cyclohexanediones with acetylenedicarboxylic acid in aqueous medium. Orbital: The Electronic Journal of Chemistry, v. 4, p. 33-38, 2012.
  25. Tozatti, C. S. S. ; Khodyuk, R. G. D.; da Silva, A. O. ; dos Santos, E. A.; Amaral, M. S.; Hamel, E.; de Lima, D. P. Synthesis and biological evaluation of biaryl analogs of antitubulin compounds. Química Nova, v. 35, p. 1758-1762, 2012.
  26. Micheletti, A. C.; Beatriz, A. Progressos Recentes na Pesquisa de Compostos Orgânicos com Potencial Atividade Antileishmanicida. Revista Virtual de Química, v. 4, p. 268-286, 2012.
  27. Almeida, N. R.; Beatriz, A.; Micheletti, A. C.; de Arruda, E. J. Ozonized vegetable oils and therapeutic properties: A review. Orbital: Electron. J. Chem. 2012, 4, 313.