Artigo aceito no JBCS: Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol-Based β-Amino Alcohol Derivatives
Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol-Based β-Amino Alcohol Derivatives
Bhaskar Reddy Manda, Avvari N. Prasad, Narendar Reddy Thatikonda, Valdemar Lacerda Jr., Layla Rosario Barbosa, Heloa Santos, Wanderson Romão, Fernando R. Pavan, Camila Maríngolo Ribeiro, Edson dos Anjos dos Santos, Maria Rita Marques, Dênis Pires de Lima, Ana Camila Micheletti,**and Adilson Beatriz*
Herein we provide a simple and efficient approach for the synthesis of amino alcohols by using cardanol and glycerol building blocks with amines under catalyst-free and mild conditions. Some of these synthesized compounds exhibited significant antimicrobial activity against S. aureus and M. tuberculosis.
Journal of the Brazilian Chemical Society – 2017 In Press